abstract：PURPOSE OF REVIEW:There is persisting controversy about tocolytic treatment for preterm labour. This review addresses this controversy by appraising the recent clinical literature. RECENT FINDINGS:Surveys of obstetricians indicate a high usage of tocolysis for preterm labour, but evidence that this treatment confers o...

journal_title：Current opinion in obstetrics & gynecology

authors： King JF

更新日期：2004-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review discusses recently published data concerning the anabolic effects of androgens on muscle and the mechanism by which testosterone regulates body composition with special emphasis on the anabolic effects of androgens on the muscles of the pelvic floor and lower urinary tract. RECENT FINDING...

journal_title：Current opinion in obstetrics & gynecology

authors： Ho MH,Bhatia NN,Bhasin S

更新日期：2004-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The recovery of immature oocytes followed by in-vitro maturation (IVM) and in-vitro fertilization is an attractive alternative to conventional in-vitro fertilization treatment in which controlled ovarian stimulation with gonadotropins is used to increase the number of available oocytes and embryos. Si...

journal_title：Current opinion in obstetrics & gynecology

authors： Chian RC,Lim JH,Tan SL

更新日期：2004-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Antenatal fetal surveillance is a field of increasing importance in modern obstetrics, especially as results in perinatal care have recently made dramatic progress. It is an evolving field, and it is no longer acceptable just to wait and see when problems arise in pregnancy. During the past few decade...

journal_title：Current opinion in obstetrics & gynecology

authors： Malcus P

更新日期：2004-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The radical surgical approach in the treatment of vulvar cancer patients has led to a favourable prognosis for the majority of patients with early stage vulvar cancer. However, morbidity is impressive, leading to more individualized treatment. The authors have reviewed the most recent literature on th...

journal_title：Current opinion in obstetrics & gynecology

authors： de Hullu JA,Oonk MH,van der Zee AG

更新日期：2004-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize results from the Women's Health Initiative trial and other recent randomized placebo-controlled trials of hormone replacement therapy, which fundamentally changed our understanding of its risks and benefits. RECENT FINDINGS:The Women's Health Initiative study for the first time provided ...

journal_title：Current opinion in obstetrics & gynecology

authors： Kocjan T,Prelevic GM

更新日期：2003-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Laparoscopy is the gold standard for the diagnosis of endometriosis but the need for visual evidence of the disease is a major stumbling-block for both effective clinical management of affected patients as well as for research into this common and debilitating reproductive disease. Laparoscopy is inva...

journal_title：Current opinion in obstetrics & gynecology

authors： Brosens I,Puttemans P,Campo R,Gordts S,Brosens J

更新日期：2003-12-01 00:00:00

abstract：PURPOSE OF REVIEW:We present an update on amenorrhea in adolescent girls and young women. Amenorrhea may herald the onset of estrogen deficiency, which can adversely affect peak bone mass and ultimate risk of osteoporosis. RECENT FINDINGS:Adolescence is a critical period for bone accretion. Important modifiable factor...

journal_title：Current opinion in obstetrics & gynecology

authors： Gordon CM,Nelson LM

更新日期：2003-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Much attention has been paid to the role of immunology in reproductive success or failure. Every step in the establishment of normal pregnancy has been implicated as a possible site of immune-mediated reproductive failure. The widespread testing of antiphospholipid, antinuclear, antithyroid, and antis...

journal_title：Current opinion in obstetrics & gynecology

authors： Kallen CB,Arici A

更新日期：2003-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Confidential enquiries of maternal deaths in the UK for 1997-1999 revealed that the number of indirect deaths from medical conditions exacerbated by pregnancy was greater than deaths from conditions directly caused by pregnancy. Indirect maternal deaths accounted for 36% of all deaths. Although neopla...

journal_title：Current opinion in obstetrics & gynecology

authors： Chandraharan E,Arulkumaran S

更新日期：2003-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Monochorionic compared with dichorionic twins have disproportionately high fetal loss rates, perinatal mortality and morbidity. This is because of the unpredictable vascular anastomoses and the often asymmetrical distribution of the single placenta between both twins. RECENT FINDINGS:The pathophysiol...

journal_title：Current opinion in obstetrics & gynecology

authors： Lewi L,Van Schoubroeck D,Gratacós E,Witters I,Timmerman D,Deprest J

更新日期：2003-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Borderline tumors of the ovary are seen commonly in obstetrics and gynecology practices. This review will outline the most recent information regarding the epidemiology, molecular pathogenesis, pathology, and clinical management of these tumors. RECENT FINDINGS:In the past, borderline ovarian tumors ...

journal_title：Current opinion in obstetrics & gynecology

authors： Crispens MA

更新日期：2003-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review was to summarize recently published clinical and animal-based studies of antenatal corticosteroids, describe current recommendations for practice, and suggest priority areas for future research. RECENT FINDINGS:A single course of antenatal corticosteroids is known to improv...

journal_title：Current opinion in obstetrics & gynecology

authors： Newnham JP,Moss TJ,Nitsos I,Sloboda DM

更新日期：2002-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Polycystic ovary syndrome is one of the most common endocrinopathies affecting premenopausal women. This review focuses on this major cause of hyperandrogenism in adolescents and young women, highlighting new diagnostic and therapeutic strategies that are under investigation. The pathophysiologic role...

journal_title：Current opinion in obstetrics & gynecology

authors： Stafford DE,Gordon CM

更新日期：2002-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Apart from histopathology, electrophysiological methods are the only tests to reveal neuromuscular involvement in the absence of gross anatomical lesions. They have played a major role in establishing the neuromuscular lesion due to vaginal delivery as a risk factor for incontinence and pelvic organ p...

journal_title：Current opinion in obstetrics & gynecology

authors： Vodusek DB

更新日期：2002-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Many minimally invasive techniques have recently been introduced for the management of uterine fibroids. The purpose of this review is to analyse recent data for techniques that are used to manage uterine fibroids. RECENT FINDINGS:Laparoscopic myomectomy has provided a minimally invasive alternative ...

journal_title：Current opinion in obstetrics & gynecology

authors： Falcone T,Bedaiwy MA

更新日期：2002-08-01 00:00:00

abstract：:Ovarian stimulation is applied during infertility management either alone or in conjunction with intrauterine insemination and assisted reproductive technologies. At the present time, the two main medications used for ovarian stimulation include an oral antiestrogen, clomiphene citrate, and injectable gonadotropins. I...

journal_title：Current opinion in obstetrics & gynecology

authors： Mitwally MF,Casper RF

更新日期：2002-06-01 00:00:00

abstract：:Mifepristone is an orally active progesterone antagonist. It can be used for both contraceptive and non-contraceptive clinical indications. It is a very effective drug for emergency contraception with a low incidence of side effects. There is a potential for mifepristone to be used as a once-a-month pill. There is a n...

journal_title：Current opinion in obstetrics & gynecology

authors： Ho PC,Yu Ng EH,Tang OS

更新日期：2002-06-01 00:00:00

abstract：:Congenital heart disease in pregnancy is increasingly common because of the advances in surgery and medical therapy which have taken place over the last 30 years, which means that more affected women are surviving into the reproductive age. Antenatal counselling needs to be tailored to the specific lesion, with pulmon...

journal_title：Current opinion in obstetrics & gynecology

authors： Lupton M,Oteng-Ntim E,Ayida G,Steer PJ

更新日期：2002-04-01 00:00:00

abstract：:This review explores the recent experience with, and the basis for, the use of selective estrogen receptor modulators to treat and prevent breast cancer. As new agents are unveiled, they will continue to be tested against tamoxifen. A number of new selective estrogen receptor modulators are in clinical development in ...

journal_title：Current opinion in obstetrics & gynecology

authors： Bentrem DJ,Jordan VC

更新日期：2002-02-01 00:00:00

abstract：:Few randomized studies have addressed the best choice of adjuvant radiation therapy after surgery for stage I endometrial cancer. Although whole pelvic radiation decreases the incidence of pelvic and vaginal cancer recurrence, there is no convincing evidence that it improves survival in women who have been completely ...

journal_title：Current opinion in obstetrics & gynecology

authors： Naumann RW

更新日期：2002-02-01 00:00:00

abstract：:Misoprostol, an orally active prostaglandin E1 analogue, has been used widely by the vaginal and oral routes for labour induction at or near term. Several recent trials have confirmed that it is highly effective. Overall caesarean section rates appear to be reduced, despite a relative increase in caesarean sections fo...

journal_title：Current opinion in obstetrics & gynecology

authors： Hofmeyr GJ

更新日期：2001-12-01 00:00:00

abstract：:Outpatient hysteroscopy has shown good correlation of findings compared with inpatient hysteroscopy, but one limitation is pain and discomfort in some women, and vasovagal reaction. Various forms of local anaesthesia have been evaluated in the past year, with controversial results, and a narrow 3.5 mm sheath hysterosc...

journal_title：Current opinion in obstetrics & gynecology

authors： Marana R,Marana E,Catalano GF

更新日期：2001-08-01 00:00:00

abstract：:The preponderance of recent data suggests that endometriosis does not adversely affect in-vitro fertilization pregnancy rates. However, many studies demonstrate impaired oocyte quality, decreased fertilization, and compromised implantation rates. Such findings give insight into the mechanisms by which endometriosis ma...

journal_title：Current opinion in obstetrics & gynecology

authors： Mahutte NG,Arici A

更新日期：2001-06-01 00:00:00

abstract：:The subdermal contraceptive implant etonogestrel (Implanon; NV Organon International, Oss, The Netherlands) exerts complex effects on the endometrium. These include direct effects on the endometrium through endometrial progestin target sites, and indirect effects through suppression of the hypothalamic-pituitary-ovari...

journal_title：Current opinion in obstetrics & gynecology

authors： Varma R,Mascarenhas L

更新日期：2001-06-01 00:00:00

abstract：:Specialized fetal echocardiography at 18 to 22 weeks for high-risk groups is well established as being sensitive and specific for most cardiac abnormalities. Early fetal echocardiography (< 16(+0) weeks, i.e. 16 weeks and 0 days) is a feasible alternative to mid second trimester scanning for families at risk of congen...

journal_title：Current opinion in obstetrics & gynecology

authors： Carvalho JS

更新日期：2001-04-01 00:00:00

abstract：:Gynecologic oncology is a rapidly growing field due to constant advances in immunohistochemistry and molecular biology. This review serves as an overview of new studies promoting the use of tumor markers and molecular biological prognostic factors in malignancies affecting women. The majority of studies focus on eithe...

journal_title：Current opinion in obstetrics & gynecology

authors： Geisler JP,Geisler HE

更新日期：2001-02-01 00:00:00

abstract：:Vaginal birth has been recognized as being potentially traumatic to the pelvic floor. It is important that contributory obstetric factors are identified and their occurrence minimized. Women who have sustained significant anal sphincter injury are at greater risk of further damage and faecal incontinence with subseque...

journal_title：Current opinion in obstetrics & gynecology

authors： Fitzpatrick M,O'Herlihy C

更新日期：2000-12-01 00:00:00

abstract：:The surgical management of hydrosalpinges is a controversial subject. Chronic pathology of the fallopian tube with distal obstruction leads to the formation of a hydrosalpinx, and is associated with very poor pregnancy rates after surgery. In these cases, in-vitro fertilization has proved to be a much better alternati...

journal_title：Current opinion in obstetrics & gynecology

authors： Mansour R,Aboulghar M,Serour GI

更新日期：2000-08-01 00:00:00

abstract：:Current ultrasound equipment allows the antenatal identification of many central nervous system anomalies from early gestation. In selected cases, special techniques (transvaginal sonography, three-dimensional ultrasound, colour Doppler) may enhance the diagnostic potential. Diagnostic accuracy, however, remains heavi...

journal_title：Current opinion in obstetrics & gynecology

authors： Pilu G,Perolo A,Falco P,Visentin A,Gabrielli S,Bovicelli L

更新日期：2000-04-01 00:00:00

abstract：:Human papillomavirus testing has been evaluated as an adjunct to cervical cytologic screening. There is a well-established association between high-risk malignant subtypes of human papillomavirus infection and the development of neoplastic change. Although human papillomavirus infection is a necessary condition for ma...

journal_title：Current opinion in obstetrics & gynecology

authors： Goodman A

更新日期：2000-02-01 00:00:00

abstract：:This review explores some of the implications for a balanced approach to the ethics of maternal participation in clinical research, from the perspective of the fetus as a patient, which is a central concept in obstetric ethics. The review therefore begins with an account of this topic, followed by an examination of so...

journal_title：Current opinion in obstetrics & gynecology

authors： Chervenak FA,McCullough LB

更新日期：1999-12-01 00:00:00

abstract：:The battle against the epidemic of sexually transmitted infections continues but the clinician has new diagnostic and therapeutic weapons. This manuscript reviews new technologies, as well as novel applications of newer methodologies, such as utilization of amplified DNA techniques for urine specimens or patient-colle...

journal_title：Current opinion in obstetrics & gynecology

authors： Biro FM

更新日期：1999-10-01 00:00:00

abstract：:Electro-stimulation has been reported to be effective in the relief of stress and urge urinary incontinence. The rates of cure and improvement brought about by pelvic floor electro-stimulation in patients with urinary incontinence are 30-50% and 60-90%, respectively. In clinical practice, vaginal, anal and surface ele...

journal_title：Current opinion in obstetrics & gynecology

authors： Yasuda K,Yamanishi T

更新日期：1999-10-01 00:00:00

abstract：:The critical role of angiogenesis in embryology and tumor biology has been recognized for more than 20 years. However, the fact that neovascularization is essential to processes in mammalian female reproduction has only recently been appreciated widely. In this review we focus on a single angiogenic growth factor, vas...

journal_title：Current opinion in obstetrics & gynecology

authors： Lebovic DI,Mueller MD,Taylor RN

更新日期：1999-06-01 00:00:00

abstract：:Our understanding of the causes, mechanisms, and prenatal management of fetal obstructive uropathy has increased significantly. Improved methods of prenatal evaluation have allowed the better selection of fetuses for invasive therapy, and studies indicate better survival and renal outcomes in carefully selected cases....

journal_title：Current opinion in obstetrics & gynecology

authors： Johnson MP,Freedman AL

更新日期：1999-04-01 00:00:00

abstract：:Immune based therapies for ovarian carcinoma continue to evolve. The current status of antibody, antibody conjugates, cytokine, cellular, and vaccine based immunotherapy is reviewed. Novel gene transfer strategies that will play an increasing important role in the evolution of immunotherapy are also discussed. ...

journal_title：Current opinion in obstetrics & gynecology

authors： Vanderkwaak TJ,Alvarez RD

更新日期：1999-02-01 00:00:00

abstract：:Studies published in the past year have attempted to model the pathophysiology of the twin-twin transfusion syndrome and also to establish the minimal diagnostic criteria for the condition. Many papers focused on treatment regimens and their sequelae. Aggressive treatment with serial amnioreduction continues to predom...

journal_title：Current opinion in obstetrics & gynecology

authors： Filkins KA,Beverly SE

更新日期：1998-12-01 00:00:00

abstract：:Neuromodulation is one option for the management of a wide variety of lower urinary tract disorders, including non-neuropathic and neuropathic bladder dysfunctions. The mechanisms of action of the reported techniques remain unclear; urodynamic changes are minimal, but symptomatic improvements are common. Although the ...

journal_title：Current opinion in obstetrics & gynecology

authors： Hasan ST,Neal DE

更新日期：1998-10-01 00:00:00

abstract：:Magnetic resonance imaging represents a new method of imaging the pelvic viscera and pelvic floor musculature. Rapid sequences allow us to perform magnetic resonance imaging dynamically during straining or pelvic floor contraction, which can elegantly demonstrate the patterns of pelvic floor prolapse. The technique is...

journal_title：Current opinion in obstetrics & gynecology

authors： Steiner RA,Healy JC

更新日期：1998-08-01 00:00:00